Combined PET/MRI Scanner

Abstract

A simultaneous dual modality PET/MRI scanner includes a magnet employed to produce a magnetic field suitable for magnetic resonance imaging, a radiofrequency coil, and a ring tomograph disposed within the magnetic field produced by the magnet. The ring tomograph contains a scintillator layer which is coupled to a detection array, which in turn is coupled to a front-end electronic array, which has a preamplifier and a shaper network for conditioning the detection signal.

Description

The imaging tools could also be used to assess the effects of therapeutic drugs, such as administering synthetic narcotics to pregnant women following surgical procedures performed on fetuses in utero. "Following such surgeries, which are becoming more common to correct congenital malformations, the mother is treated with narcotics for pain--and anesthesiologists are relying on the mother transferring the pain medication to the fetus via the placenta. But we actually do not know if what we give is sufficient to 'satisfy' the pain level of the fetus," said Benveniste, who is also a professor of anesthesiology at Stony Brook University.

Though other scientists have attempted to use PET to noninvasively monitor maternal-fetal drug exchange and pharmacokinetics (how quickly a drug is taken up and distributed among the body's organs), the PET technique alone did not provide adequate anatomical detail of the tiny fetal organs. The current study combined PET with high-resolution magnetic resonance imaging (MRI) to track cocaine pharmacokinetics down to the level of the placenta and individual regions of the fetal brain.

    Images

More Details

From the patent abstract: A combined PET/MRI scanner generally includes a magnet for producing a magnetic field suitable for magnetic resonance imaging, a radiofrequency (RF) coil disposed within the magnetic field produced by the magnet and a ring tomograph disposed within the magnetic field produced by the magnet. The ring tomograph includes a scintillator layer for outputting at least one photon in response to an annihilation event, a detection array coupled to the scintillator layer for detecting the at least one photon outputted by the scintillator layer and for outputting a detection signal in response to the detected photon and a front-end electronic array coupled to the detection array for receiving the detection signal, wherein the front-end array has a preamplifier and a shaper network for conditioning the detection signal.

Marketing Information

Applications

A dual modality PET/MRI scanner will be extremely useful in studies such as in vivo analysis of complex metabolic systems, validation of functional MRI techniques for brain mapping and in development of new pharmaceuticals such as psycho-active drugs.

Advantages

The technology provides a MRI scanner combined with a PET scanner whose output is not detrimentally affected by the magnetic fields produced by the MRI scanner. The technology allows one to simultaneously realize the diagnostic benefits of using PET the MRI imaging techniques.

Tech Transfer Details

  • 12/31/1969
  • Poornima Upadhya (631) 344-4711
  • BNL
  • 11/9/2011

Details

  • Patent
  • BNL
  • Exclusive and Non-Exclusive
  • 10/14/2004
  • David J. Schlyer; Craig Woody; William Rooney; Paul Vaska; Sean Stoll; Jean-francois Pratte; Paul O’connor
  • Patent #7286867
  • 0 : Not Set/Not Applicable

Available for Licensing 

• Non-Exclusive 
• Exclusive






Sharing and Social Links

Adding...

Adding...

There are no comments for Combined PET/MRI Scanner yet.

Loading comment form.